Deadline.com reports Gandolfini suffered a sudden heart attack while attending the 59th Taormina Film Festival in Sicily. He was scheduled to participate in a festival event this weekend with Italian director Gabriele Muccino.
Gandolfini appeared in several movies and TV series, gaining his first recognition as a hitman in 1993's "True Romance.”
He gained international fame as the “Sopranos” mob boss Tony Soprano, winning three Emmys during the show's six-season run.
Gandolfini also appeared in films such as "Get Shorty," "The Mexican" and "Zero Dark Thirty."
He is survived by his wife, Deborah Lin, who gave birth to the couple's daughter in October 2012. He also has a teenage son from a previous marriage.