Actor Kelsey Grammer is heading back to TV in the new Starz drama, "Boss."

Grammer plays Mayor Tom Kane, who sits at the center of Chicago's web of power and uses deception and questionable morality to achieve his goals. Despite being the most effective mayor in recent history, a degenerative brain disorder is ripping everything away from him. He can't trust his memory, his closest allies, or even himself.

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The show also stars Connie Nielsen as Kane's wife, Kathleen Robertson as his advisor, and Hannah Ware as his estranged daughter.

"Boss" premieres on Starz this October.

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