'Family' Man Seth MacFarlane

Seth MacFarlane is the brain behind "Family Guy" -- and he also voices the popular characters Peter, Brian, Quagmire and Stewie! Now the creative force driving the tube's most controversial show is right here at "Extra!"

The comedic genius immediately went to work, blasting away at today's most burning issues - and opened up about how one fortuitous mistake ended up saving his life.