2015 was a banner year for Schumer, who made headlines with her huge box-office success hit “Trainwreck” and her budding friendship with Jenner Lawrence. The biggest and most memorable moment for her was appearing on “SNL.” She said, "Hosting 'Saturday Night Live' was the highlight of my year. It was a dream come true.”
Schumer has used her newfound fame to raise awareness on gender equality, female empowerment, and gun control. Watch a video of Amy and many other stars, including Sofia Vergara and Jennifer Aniston, spreading the word to "end gun violence."
To find out who else made the list, pick up the new issue of People magazine, on newsstands Friday.