It's still the number one sitcom, but can the show go on without its number one star? On Charlie Sheen's webcast Monday night, he declared, "It's my life... it's about winning."

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Winning would be difficult for Sheen if CBS pulled the plug on "Two and a Half Men," since he would miss out on a staggering $30-million in salary alone -- and the network would be turning down $250-million!

The buzz around town is that John Stamos, Jerry O'Connell, Rob Lowe, and Robert Downey Jr. are all possible replacements. If Sheen is replaced, the show may not make him the lead character. Variety's Cynthia Littleton speculates, "The suspicion is it will lean much more on the two existing stars - the one and a half men -- John Cryer and Angus T. Jones."

Whether "Two and a Half Men" will make it may not be revealed until CBS announces their fall lineup in May.

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