Salma Hayek's frantic reaction to a snake interrupting the "Grown Ups" junket stands as "Extra's" best story of 2010!

As "Extra's" Terri Seymour chatted up "Grown Ups" stars Salma, Maria Bello and Maya Rudolph last June, they got an expected guest -- a harmless but rather large snake -- which sent the girls into a tizzy, as they scrambled to get away from the reptile, especially the frantic, screaming Salma.

"It was like a python. It was thick. Its head was like this like a cobra!" Bello exclaimed afterward.

Check out the hilarious raw reactions!

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