The "Stand Up to Cancer" telethon Friday was an opportunity for Hollywood A-listers to stand up for those who have had or are now battling the disease, including Michael Douglas.
"He's one of my favorite actors ever," actor Rob Lowe told "Extra's" Lauren Sanchez. "One of my favorite people ever, and he's got everything going for him. Everything."
"Stand Up to Cancer" Co-Founder Katie Couric added, "I think he's remarkably courageous. I think he's so brave to talk candidly and openly about his situation."
Many celebrities had their own personal stories to tell. "I lost a brother to leukemia when he was 4 and I was 10," confessed supermodel Cindy Crawford. "Then two years ago my sister got diagnosed with thyroid cancer. Fortunately, she's doing really well."
"Modern Family's" Sofia Vergara admitted she had thyroid cancer but is now in remission. "I know what it is when you're young and healthy for someone to tell you 'you have cancer'." Her co-star, Eric Stonestreet, said his mom "beat two forms of cancer in the last 8 years."
A pregnant Christina Applegate, who endured her own battle with breast cancer, finds inspiration in her friend and fellow survivor Maura Tierney.
"I'm so excited to see Maura here tonight. She's just a vision of loveliness and she's proof that you can kick its ass."
If you missed the televised live event Friday, you can watch it here at ABC.com.
For donations and ways you can help, visit StandUp2Cancer.org.