"Melissa and Tammy Etheridge are saddened to announce that they are now separated," Melissa's rep confirms to "Extra."The pair added a joint statement: "We ask for consideration and respect for our family as we go through this difficult period."
Melissa, 48, and Tammy, 35, exchanged vows in a 2003 Malibu ceremony that was featured on ABC's "InStyle Celebrity Weddings." Tammy gave birth to their twins; son Miller and daughter Johnnie Rose in 2006, after helping Melissa get through her battle with breast cancer.
Etheridge has two children with former partner Julie Cypher.