"The one who I always notice is Cate Blanchett," he admitted. "They have paparazzi pictures of her going to the laundry mat or something, and she looks gorgeous!"
Now Isaac is going wild with the second season of his signature talk show, and with guests like Diane Lane and "Deal or No Deal's" Howie Mandel, it's going to be a star-studded affair.
From makeup makeovers with Leah Remini, who said it's "unacceptable" to even lounge sans her lipstick and lashes, to vintage shopping with Haylie Duff, you can never predict what Isaac is going to say.
Check out the daring fashionista talk about what he knows best, as Isaac debuts on the Style Channel Monday night!